Medical Director, Clinical Development(Nephrology)

About Jade Biosciences

Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade's lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade's pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn.

Role Overview

We are seeking an experienced and mission-driven Medical Director in Clinical Development to lead and support clinical programs in nephrology, with a focus on rare or immune-mediated kidney diseases. This role is ideal for a physician-scientist who thrives in a small biotech environment where agility, cross-functional collaboration, and scientific leadership are essential. The Medical Director will play a key role in advancing Jade's pipeline through clinical development. This newly created position will report to the Executive Medical Director of Clinical Development. This is a fully remote role and will require some travel.

Key Responsibilities

Clinical Development

• Lead the design, execution, and oversight of clinical trials in nephrology, including protocol development, study monitoring, and data interpretation.
• Serve as Medical Monitor for ongoing trials, ensuring patient safety and scientific integrity.
• Collaborate with clinical operations, regulatory, and biometrics teams to ensure trial success and compliance.
• Educate and advise clinical sites/investigators to support enrollment and optimal study conduct, including presenting at investigator meetings and/or